Carbon nanotube-ionic liquid nanocomposite modified carbon-ceramic electrode for determination of dopamine in real samples

• Published in: Central European journal of chemistry 2013-07, Vol.11 (7), p.1172-1186
• Main Authors: Majidi, Mir Reza, Baj, Reza Fadakar Bajeh, Naseri, Abdolhossein
• Format: Article
• Language: English
• Subjects: Biochemistry; Biological and Medical Physics; Biophysics; Carbon-ceramic electrode; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Dopamine; Geochemistry; Ionic liquid; Multi walled carbon nanotubes; Nanocomposite; Research Article
• ISSN: 1895-1066; 2391-5420; 1644-3624; 2391-5420
• DOI: 10.2478/s11532-013-0251-2

Room temperature 1-butyl-3-methylimidazolium tetraflouroborate ([BMIM][BF 4 ]) ionic liquid was employed for dispersion of multi walled carbon nanotubes (MWCNTs) and the formation of nanocomposite on the surface of a carbon-ceramic electrode. The surface of the modified electrode was characterized using scanning electron microscopy and electrochemical impedance spectroscopy. The modified electrode exhibited excellent electrochemical activity to oxidation of dopamine (DA); whereas electro oxidation of ascorbic acid (AA) was not seen and electro oxidation of uric acid (UA) appeared at a more positive potential than DA. The multi walled carbon nanotube-ionic liquid nanocomposite modified carbon-ceramic electrode was used for the selective determination of DA in the presence of high levels of AA and UA using differential pulse voltammetry. The calibration curve for DA was linear in the range of 3.00 to 130 µM with the detection limit (S/N=3) of 0.87 µM. The present electrode was successfully applied to the determination of DA in some commercial pharmaceutical samples and human blood serum.