Synthesis of cinnamic acid-derived 4,5-dihydrooxazoles

A range of cinnamic units containing 4,5-dihydrooxazoles was prepared using two different synthetic routes. The first method was based on the transformation of substituted cinnamic or benzoic acids to 2-styryl-4,5-dihydrooxazoles. Several derivatives containing phenolic groups were prepared in this...

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Bibliographic Details
Published in:Chemical papers 2013-11, Vol.67 (11), p.1424-1432
Main Authors: Kronek, Juraj, Nedelčev, Tomáš, Mikulec, Marcel, Kleinová, Angela, Lustoň, Jozef
Format: Article
Language:English
Subjects:
2-oxazolines
4,5-dihydrooxazole
Biochemistry
Biotechnology
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
cinnamic acid derivatives
conjugated unsaturated bond
Industrial Chemistry/Chemical Engineering
Materials Science
Medicinal Chemistry
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Summary:A range of cinnamic units containing 4,5-dihydrooxazoles was prepared using two different synthetic routes. The first method was based on the transformation of substituted cinnamic or benzoic acids to 2-styryl-4,5-dihydrooxazoles. Several derivatives containing phenolic groups were prepared in this manner. The second approach consisted of a reaction between the 4,5-dihydrooxazole moiety and double bond-containing compounds. These compounds contain two or more reactive centres capable of providing polymerisations and also organic reactions.
ISSN:0366-6352
1336-9075
1336-9075
DOI:10.2478/s11696-013-0405-x