Assay of cortisol and its metabolite in the rat urine by HPLC-MS method

A technique has been developed for the assay of cortisol and its metabolite (6-β-hydroxycortisol) in the rat urine. Analysis was performed using high-performance liquid chromatography with mass-selective detector. The limits of the quantification of cortisol and its metabolite are 1.0 and 2.5 ng/mL,...

Full description

Saved in:
Bibliographic Details
Published in:Moscow University chemistry bulletin 2013, Vol.68 (1), p.51-53
Main Authors: Emel’yanov, M. I., Smirnov, V. V., Litvin, A. A., Kolyvanov, G. B., Blynskaya, E. V., Kondakov, S. E.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A technique has been developed for the assay of cortisol and its metabolite (6-β-hydroxycortisol) in the rat urine. Analysis was performed using high-performance liquid chromatography with mass-selective detector. The limits of the quantification of cortisol and its metabolite are 1.0 and 2.5 ng/mL, respectively.
ISSN:0027-1314
1935-0260
DOI:10.3103/S0027131413010033