Loading…
Reconstruction of the spatial structure of plant phosphatases types 1 and 2A in complexes with okadaic acid
Homology modeling based on the known spatial structures of Homo sapiens protein phosphatases types 1 and 2A was implemented. The spatial structures of human protein phosphatases and their plant homologs from Arabidopsis thaliana were predicted. The quality of the models was confirmed by the root mea...
Saved in:
Published in: | Cytology and genetics 2011-06, Vol.45 (3), p.153-162 |
---|---|
Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | Homology modeling based on the known spatial structures of
Homo sapiens
protein phosphatases types 1 and 2A was implemented. The spatial structures of human protein phosphatases and their plant homologs from
Arabidopsis thaliana
were predicted. The quality of the models was confirmed by the root mean square deviations of the atoms and conformational analysis results. The sites of okadaic acid bindings in the molecules of plant protein phosphatases (types 1 and 2A) were verified by the data of comparative analyses and molecular dynamics. |
---|---|
ISSN: | 0095-4527 1934-9440 |
DOI: | 10.3103/S0095452711030108 |