Inflammatory and endothelial markers during the menstrual cycle

Background The menstrual cycle exhibits a pattern of repeated inflammatory activity. The present study aims to evaluate inflammatory and endothelial markers during the two phases of a menstrual cycle. Methods The study cohort consisted of 102 women with regular menstrual cycles. Inflammatory and end...

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Bibliographic Details
Published in:Scandinavian journal of clinical and laboratory investigation 2016, Vol.76 (3), p.190-194
Main Authors: Chaireti, Roza, Lindahl, Tomas L., Byström, Birgitta, Bremme, Katarina, Larsson, Anders
Format: Article
Language:English
Subjects:
Adult
Biomarkers - blood
Female
Follicular Phase - blood
Follicular Phase - immunology
Humans
Inflammation
Inflammation Mediators - blood
Luteal Phase - blood
Luteal Phase - immunology
Medicin och hälsovetenskap
menstrual cycle
pentraxin
Sex Hormone-Binding Globulin - metabolism
Young Adult
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Summary:Background The menstrual cycle exhibits a pattern of repeated inflammatory activity. The present study aims to evaluate inflammatory and endothelial markers during the two phases of a menstrual cycle. Methods The study cohort consisted of 102 women with regular menstrual cycles. Inflammatory and endothelial markers (interleukin-6 [IL-6], pentraxin-3 [PTX-3], hs-C reactive protein [hs-CRP], sE-selectin, sP-selectin, intracellular and vascular cell adhesion molecules [ICAM-1 and VCAM-1] and cathepsins L, B and S) were measured during the early follicular and the late luteal phase of a normal menstrual cycle. Results Pentraxin-3 (PTX-3) and hs-CRP were significantly higher during the follicular phase compared to the luteal phase (p 
ISSN:0036-5513
1502-7686
1502-7686
DOI:10.3109/00365513.2015.1129670