Comparing Anatomical Pattern of Topical Anti-Glaucoma Medications Associated Lacrimal Obstruction with a Control Group

Purpose: To compare the anatomical pattern of lacrimal drainage system obstruction (LDSO) associated with topical anti-glaucoma medications (AGM) with a control group. Methods: In a cross-sectional controlled study, case group included patients on topical anti-glaucoma medications and control group...

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Bibliographic Details
Published in:Orbit (Amsterdam) 2010-04, Vol.29 (2), p.65-69
Main Authors: Kashkouli, Mohsen Bahmani, Pakdel, Farzad, Hashemi, Masih, Ghaempanah, Mohammad Jafar, Rezaee, Reza, Kaghaz-Kanani, Reza, Ahadian, Ali
Format: Article
Language:English
Subjects:
Administration, Topical
Adolescent
Adult
Aged
Aged, 80 and over
Anti-glaucoma medication
Antihypertensive Agents - adverse effects
Cross-Sectional Studies
Female
Glaucoma
Glaucoma - drug therapy
Humans
Lacrimal drainage
Lacrimal Duct Obstruction - chemically induced
Lacrimal Duct Obstruction - diagnosis
Lacrimal obstruction
Male
Middle Aged
Nasolacrimal Duct - drug effects
Nasolacrimal Duct - pathology
Ophthalmic Solutions - adverse effects
Young Adult
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Summary:Purpose: To compare the anatomical pattern of lacrimal drainage system obstruction (LDSO) associated with topical anti-glaucoma medications (AGM) with a control group. Methods: In a cross-sectional controlled study, case group included patients on topical anti-glaucoma medications and control group included patients with no history of glaucoma, free of ocular disease, and not using topical medications. Data recording, eye examination, and categorization of patients into case and control groups were performed by a senior ophthalmology resident. Diagnostic probing and irrigation test was performed by an oculoplastic surgeon who was masked to the patients' data. Chi-square (X2) and tests were used to assess the effect of sex and systemic diseases, as well as logistic regression analysis with intra-cluster correlation for the effect of topical anti-glaucoma medications on lacrimal drainage system, and then independent sample t-tests to compare the mean ages, plus the binary logistic regression test for the effect of increasing age on LDSO. Results: There were 128 eyes of 96 patients in the case and 277 eyes of 172 patients in the control group. Two groups were similar regarding to the age, sex, and associated systemic disorders (0.3
ISSN:0167-6830
1744-5108
DOI:10.3109/01676830903324284