Clearance approach in hyperinsulinemic-euglycemic clamp evaluation in lean and obese subjects

Abstract Purpose/Aim: The main aim of this study was to propose a method to express whole body insulin sensitivity as estimated by a hyperinsulinemic-euglycemic clamp (HEC) as a dimensionless parameter. Materials and methods: Two groups of subjects were examined: The first group was comprised of sev...

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Bibliographic Details
Published in:Endocrine research 2015-01, Vol.40 (3), p.156-159
Main Authors: Dedik, Ladislav, Chrenova, Jana, Rausova, Zuzana, Mingrone, Geltrude, Penesova, Adela
Format: Article
Language:English
Subjects:
Adult
Blood Glucose - metabolism
Body Mass Index
Clearance
Female
glucose
Glucose Clamp Technique - methods
Glucose Tolerance Test
Humans
hyperinsulinemic-euglycemic clamp
insulin
Insulin - blood
Insulin Resistance - physiology
M/I
Male
Obesity - metabolism
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Summary:Abstract Purpose/Aim: The main aim of this study was to propose a method to express whole body insulin sensitivity as estimated by a hyperinsulinemic-euglycemic clamp (HEC) as a dimensionless parameter. Materials and methods: Two groups of subjects were examined: The first group was comprised of seven healthy lean volunteers with BMI
ISSN:0743-5800
1532-4206
DOI:10.3109/07435800.2014.982325