Decreased estimated glomerular filtration rate (eGFR) is not an independent risk factor of arterial stiffness in Chinese women

Abstract Recent studies suggest that decreased estimated glomerular filtration rate (eGFR) and uric acid (UA) may be independent risk factors for arterial stiffness (AS). As serum UA level is linked to renal function, we hypothesize that decreased eGFR may be not an independent risk factor of AS, bu...

Full description

Saved in:
Bibliographic Details
Published in:Blood pressure 2013-04, Vol.22 (2), p.73-79
Main Authors: Xie, Xiang, Ma, Yi-Tong, Yang, Yi-Ning, Li, Xiao-Mei, Fu, Zhen-Yan, Ma, Xiang, Chen, Bang-Dang, Liu, Fen, Huang, Ying, Zheng, Ying-Ying, Yu, Zi-Xiang, Chen, You, Huang, Ding
Format: Article
Language:English
Subjects:
Adult
arterial stiffness
Asian Continental Ancestry Group
Blood Flow Velocity
Blood Glucose - analysis
Blood Pressure
Cardiovascular System - metabolism
Cardiovascular System - physiopathology
Elasticity
estimate glomerular filtration rate
Fasting
fasting blood glucose
Female
Glomerular Filtration Rate
Health Surveys
Humans
Kidney - metabolism
Kidney - physiopathology
Male
Middle Aged
Pulsatile Flow
pulse wave velocity
Risk Factors
uric acid
Uric Acid - blood
Vascular Stiffness
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Recent studies suggest that decreased estimated glomerular filtration rate (eGFR) and uric acid (UA) may be independent risk factors for arterial stiffness (AS). As serum UA level is linked to renal function, we hypothesize that decreased eGFR may be not an independent risk factor of AS, but may be related to UA level. In this study, we aimed to validate this hypothesis in a large community-based Chinese population. A total of 13,899 people were selected from the Cardiovascular Risk Survey (CRS) from October 2007 to March 2010. Pulse wave velocity (PWV) was calculated using the established methods. The relationships between eGFR, fasting blood glucose (FBG), UA and PWV were analyzed with multivariate linear regression. We found that PWV was significantly correlated to FBG (r = 0.173, p
ISSN:0803-7051
1651-1999
DOI:10.3109/08037051.2012.707308