Evaluation of Subfoveal Choroidal Thickness in Children with Type 1 Diabetes Mellitus: An EDI-OCT Study

• Published in: Seminars in ophthalmology 2014-01, Vol.29 (1), p.27-31
• Main Authors: Sayin, Nihat, Kara, Necip, Pirhan, Dilara, Vural, Asli, Ersan, Hatice Bilge Araz, Onal, Hasan, C nar, Simge
• Format: Article
• Language: English
• Subjects: Adolescent; Blood Glucose - metabolism; Child; Child, Preschool; Choroid - pathology; Diabetes Mellitus, Type 1 - complications; Diabetes type 1; Diabetic Retinopathy - complications; Female; Fovea Centralis; Glycated Hemoglobin A - metabolism; Humans; Male; optical coherence tomography; Prospective Studies; subfoveal choroidal thickness; Tomography, Optical Coherence
• ISSN: 0882-0538; 1744-5205
• DOI: 10.3109/08820538.2013.838279

Abstract Purpose: To evaluate the subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in children with type 1 diabetes without diabetic retinopathy. Methods: In this prospective and comparative study, 41 diabetic children without diabetic retinopathy and 42 age-matched healthy subjects were enrolled. The SFCT was measured by EDI-OCT. Correlations between SFCT and diabetic parameters such as fasting glucose level, HbA1c, age, or duration of diabetes were also evaluated. Results: The mean SFCT value was 375.3 ± 66.5 μm in the eyes with diabetes and 356.4 ± 52.0 μm in the control group. The SFCT was not correlated with fasting glucose level, HbA1c, age, or duration of diabetes. Conclusion: This study showed that SFCT of diabetic children are similar to those of healthy controls. In addition, SFCT are not affected by fasting glucose level, HbA1c, age, or duration of diabetes.