Exfoliative cytology for diagnosing oral cancer

Abstract Exfoliative cytology is a minimally invasive technique for obtaining oral cell specimens from patients for diagnostic purposes. Classical applications of oral cytology studies, such as oral candidiasis, have been extended to include oral precancerous and cancerous lesions. A number of analy...

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Bibliographic Details
Published in:Biotechnic & histochemistry 2010, Vol.85 (3), p.177-187
Main Authors: Pérez-Sayánsm, M, Somoza-Martín, JM, Barros-Angueira, F, Reboiras-López, MD, Gándara-Vila, P, Rey, JM Gándara, García-García, A
Format: Article
Language:English
Subjects:
Biomarkers, Tumor
Humans
Immunohistochemistry
liquid-based cytology
molecular analysis
Mouth Mucosa - pathology
Mouth Neoplasms - diagnosis
Mouth Neoplasms - pathology
oral cancer
oral cytology
quantitative cytomorphologyr
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Summary:Abstract Exfoliative cytology is a minimally invasive technique for obtaining oral cell specimens from patients for diagnostic purposes. Classical applications of oral cytology studies, such as oral candidiasis, have been extended to include oral precancerous and cancerous lesions. A number of analytical methods are available for studying cytology specimens. The development of molecular analysis techniques, the oral cancer etiopathogenic process, and improvements in liquid-based exfoliative cytology are leading to renewed interest in exfoliative cytology. Results sometimes are disputed, so the aim of our review was to clarify the applicability of exfoliative cytology to the diagnosis of oral precancerous and cancerous lesions.
ISSN:1052-0295
1473-7760
DOI:10.3109/10520290903162730