Fibroblast growth factor-2 and vascular endothelial growth factor expression in the ileocecal region of quail (Coturnix coturnix japonica)

Abstract We undertook this study to immunolocalize in quail vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF-2) in the ileocecal region, which is a significant entry point for intestinal immunity. Diffuse cytoplasmic reaction for FGF-2 and VEGF was observed in the epitheli...

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Bibliographic Details
Published in:Biotechnic & histochemistry 2010, Vol.85 (3), p.189-193
Main Authors: Harem, MK, Harem, IS, Sozmen, M, Sari, EK
Format: Article
Language:English
Subjects:
Animals
Cecum - immunology
Coturnix
Coturnix coturnix japonica
expression
FGF-2
Fibroblast Growth Factor 2 - metabolism
Gene Expression Profiling
Gene Expression Regulation
ileocecal region
Ileum - immunology
Immunohistochemistry
Male
quail
Quail - metabolism
Vascular Endothelial Growth Factor A - metabolism
VEGF
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Summary:Abstract We undertook this study to immunolocalize in quail vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF-2) in the ileocecal region, which is a significant entry point for intestinal immunity. Diffuse cytoplasmic reaction for FGF-2 and VEGF was observed in the epithelial cells of the distal ileum and proximal cecal mucosa. VEGF immunoreactive cells, which give strong intracytoplasmic immunoreaction, were observed in the lamina propria of both intestinal parts. FGF-2 immunoreactive cells were seen in the lamina propria and germinative centers of lymph follicles in the cecum mucosa. Expressions of FGF-2 and VEGF in healthy quail intestines indicate that these factors have physiological roles in quail.
ISSN:1052-0295
1473-7760
DOI:10.3109/10520290903297510