No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups: An 8-year follow-up of 81 patients from a previously reported controlled trial

• Published in: Acta orthopaedica 2013-12, Vol.84 (6), p.544-548
• Main Authors: Valancius, Kestutis, Søballe, Kjeld, Nielsen, Poul T, Laursen, Mogens B
• Format: Article
• Language: English
• ISSN: 1745-3674; 1745-3682
• DOI: 10.3109/17453674.2013.854665

Background and purpose Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the performance of HA- and porous-coated acetabular cups in a prospective randomized trial. Methods This was an 8-year follow-up study of our previously published prospective randomized study to compare clinical outcomes, survival, periprosthetic bone mineral density, migration, and wear rates of HA- and porous-coated acetabular cups. Dual X-ray absorptiometry (DXA) and Ein Bild Roentgen Analyse (EBRA) measurements were used. 100 patients who underwent unilateral cementless total hip arthroplasty were randomized to either porous-coated cups or HA-coated cups. Patients were examined preoperatively and at 3, 6, and 9 months, and also 1, 3, and 8 years after surgery. 81 patients were available for 8-year follow-up, 40 with porous-coated cups and 41 with HA-coated cups. Results Age, sex, bone mineral density, and clinical results (Harris hip score) were similar in the 2 groups. The survival, wear, and migration patterns of the cups were also similar in both groups. The results of periprosthetic bone mineral density scans in region of interest 2 was in favor of the porous-coated cups, but there were no differences between the 2 groups in all the remaining regions of interest. Interpretation HA coating had no statistically significant effect on clinical results, survival, wear, or migration at the 8-year follow-up.