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A case of immunoglobulin G4-related chronic sclerosing sialadenitis and dacryoadenitis associated with tuberculosis
Abstract We describe a 64-year-old woman with chronic sclerosing sialadenitis and dacryoadenitis, which developed during treatment for cervical lymph node tuberculosis. Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lac...
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Published in: | Modern rheumatology 2009-02, Vol.19 (1), p.87-90 |
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container_title | Modern rheumatology |
container_volume | 19 |
creator | Kawano, Mitsuhiro Yamada, Kazunori Kakuchi, Yasushi Ito, Kiyoaki Hamano, Ryoko Fujii, Hiroshi Inoue, Ryo Matsumura, Masami Takahira, Masayuki Zen, Yoh Yachie, Akihiro Nakashima, Akikatsu Yamagishi, Masakazu |
description | Abstract
We describe a 64-year-old woman with chronic sclerosing sialadenitis and dacryoadenitis, which developed during treatment for cervical lymph node tuberculosis. Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lacrimal gland showed inflammation, with abundant lymphoid follicles with fibrosis and granuloma without caseous necrosis. Immunohistological examination of a repeat biopsy specimen showed abundant immunoglobulin (Ig) G4-positive plasma cell infiltration. Corticosteroid therapy improved the salivary gland swelling without reactivation of the tuberculosis. This case suggests that an abnormal immunological reaction to tuberculosis may be one of the etiological candidates for IgG4-related disease. |
doi_str_mv | 10.3109/s10165-008-0127-z |
format | article |
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We describe a 64-year-old woman with chronic sclerosing sialadenitis and dacryoadenitis, which developed during treatment for cervical lymph node tuberculosis. Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lacrimal gland showed inflammation, with abundant lymphoid follicles with fibrosis and granuloma without caseous necrosis. Immunohistological examination of a repeat biopsy specimen showed abundant immunoglobulin (Ig) G4-positive plasma cell infiltration. Corticosteroid therapy improved the salivary gland swelling without reactivation of the tuberculosis. This case suggests that an abnormal immunological reaction to tuberculosis may be one of the etiological candidates for IgG4-related disease.</description><identifier>ISSN: 1439-7595</identifier><identifier>EISSN: 1439-7609</identifier><identifier>DOI: 10.3109/s10165-008-0127-z</identifier><language>eng</language><publisher>Informa Healthcare</publisher><ispartof>Modern rheumatology, 2009-02, Vol.19 (1), p.87-90</ispartof><rights>2009 Japan College of Rheumatology 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1950-6d1071575ec8832e65cb3c8b4c630878ede484e6536fb442d3ea342fb2e961a3</citedby><cites>FETCH-LOGICAL-c1950-6d1071575ec8832e65cb3c8b4c630878ede484e6536fb442d3ea342fb2e961a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Kawano, Mitsuhiro</creatorcontrib><creatorcontrib>Yamada, Kazunori</creatorcontrib><creatorcontrib>Kakuchi, Yasushi</creatorcontrib><creatorcontrib>Ito, Kiyoaki</creatorcontrib><creatorcontrib>Hamano, Ryoko</creatorcontrib><creatorcontrib>Fujii, Hiroshi</creatorcontrib><creatorcontrib>Inoue, Ryo</creatorcontrib><creatorcontrib>Matsumura, Masami</creatorcontrib><creatorcontrib>Takahira, Masayuki</creatorcontrib><creatorcontrib>Zen, Yoh</creatorcontrib><creatorcontrib>Yachie, Akihiro</creatorcontrib><creatorcontrib>Nakashima, Akikatsu</creatorcontrib><creatorcontrib>Yamagishi, Masakazu</creatorcontrib><title>A case of immunoglobulin G4-related chronic sclerosing sialadenitis and dacryoadenitis associated with tuberculosis</title><title>Modern rheumatology</title><description>Abstract
We describe a 64-year-old woman with chronic sclerosing sialadenitis and dacryoadenitis, which developed during treatment for cervical lymph node tuberculosis. Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lacrimal gland showed inflammation, with abundant lymphoid follicles with fibrosis and granuloma without caseous necrosis. Immunohistological examination of a repeat biopsy specimen showed abundant immunoglobulin (Ig) G4-positive plasma cell infiltration. Corticosteroid therapy improved the salivary gland swelling without reactivation of the tuberculosis. This case suggests that an abnormal immunological reaction to tuberculosis may be one of the etiological candidates for IgG4-related disease.</description><issn>1439-7595</issn><issn>1439-7609</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNp9kMFKAzEURQdRsFY_wF1-IJpMkpkEV6VoFQpuug-ZzJtOSppIMoO0X-_UKu5cvceFc7mcorin5IFRoh4zJbQSmBCJCS1rfLwoZpQzheuKqMvfXyhxXdzkvCOECSXVrMgLZE0GFDvk9vsxxK2PzehdQCuOE3gzQItsn2JwFmXrIcXswhZlZ7xpIbjBZWRCi1pj0yH-RTlH677pTzf0aBgbSHb0E51vi6vO-Ax3P3debF6eN8tXvH5fvS0Xa2ypEgRXLSU1FbUAKyUroRK2YVY23FaMyFpCC1zyKWZV13BetgwM42XXlKAqati8oOdaO23OCTr9kdzepIOmRJ-k6bM0PUnTJ2n6ODFPZ8aFLqa96cH4obcmgd7FMYVp7j_0F-3hdk4</recordid><startdate>200902</startdate><enddate>200902</enddate><creator>Kawano, Mitsuhiro</creator><creator>Yamada, Kazunori</creator><creator>Kakuchi, Yasushi</creator><creator>Ito, Kiyoaki</creator><creator>Hamano, Ryoko</creator><creator>Fujii, Hiroshi</creator><creator>Inoue, Ryo</creator><creator>Matsumura, Masami</creator><creator>Takahira, Masayuki</creator><creator>Zen, Yoh</creator><creator>Yachie, Akihiro</creator><creator>Nakashima, Akikatsu</creator><creator>Yamagishi, Masakazu</creator><general>Informa Healthcare</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200902</creationdate><title>A case of immunoglobulin G4-related chronic sclerosing sialadenitis and dacryoadenitis associated with tuberculosis</title><author>Kawano, Mitsuhiro ; Yamada, Kazunori ; Kakuchi, Yasushi ; Ito, Kiyoaki ; Hamano, Ryoko ; Fujii, Hiroshi ; Inoue, Ryo ; Matsumura, Masami ; Takahira, Masayuki ; Zen, Yoh ; Yachie, Akihiro ; Nakashima, Akikatsu ; Yamagishi, Masakazu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1950-6d1071575ec8832e65cb3c8b4c630878ede484e6536fb442d3ea342fb2e961a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kawano, Mitsuhiro</creatorcontrib><creatorcontrib>Yamada, Kazunori</creatorcontrib><creatorcontrib>Kakuchi, Yasushi</creatorcontrib><creatorcontrib>Ito, Kiyoaki</creatorcontrib><creatorcontrib>Hamano, Ryoko</creatorcontrib><creatorcontrib>Fujii, Hiroshi</creatorcontrib><creatorcontrib>Inoue, Ryo</creatorcontrib><creatorcontrib>Matsumura, Masami</creatorcontrib><creatorcontrib>Takahira, Masayuki</creatorcontrib><creatorcontrib>Zen, Yoh</creatorcontrib><creatorcontrib>Yachie, Akihiro</creatorcontrib><creatorcontrib>Nakashima, Akikatsu</creatorcontrib><creatorcontrib>Yamagishi, Masakazu</creatorcontrib><collection>CrossRef</collection><jtitle>Modern rheumatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kawano, Mitsuhiro</au><au>Yamada, Kazunori</au><au>Kakuchi, Yasushi</au><au>Ito, Kiyoaki</au><au>Hamano, Ryoko</au><au>Fujii, Hiroshi</au><au>Inoue, Ryo</au><au>Matsumura, Masami</au><au>Takahira, Masayuki</au><au>Zen, Yoh</au><au>Yachie, Akihiro</au><au>Nakashima, Akikatsu</au><au>Yamagishi, Masakazu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of immunoglobulin G4-related chronic sclerosing sialadenitis and dacryoadenitis associated with tuberculosis</atitle><jtitle>Modern rheumatology</jtitle><date>2009-02</date><risdate>2009</risdate><volume>19</volume><issue>1</issue><spage>87</spage><epage>90</epage><pages>87-90</pages><issn>1439-7595</issn><eissn>1439-7609</eissn><abstract>Abstract
We describe a 64-year-old woman with chronic sclerosing sialadenitis and dacryoadenitis, which developed during treatment for cervical lymph node tuberculosis. Anti-tuberculosis treatment did not improve the swelling in the lacrimal and submandibular glands, and a biopsy specimen of the lacrimal gland showed inflammation, with abundant lymphoid follicles with fibrosis and granuloma without caseous necrosis. Immunohistological examination of a repeat biopsy specimen showed abundant immunoglobulin (Ig) G4-positive plasma cell infiltration. Corticosteroid therapy improved the salivary gland swelling without reactivation of the tuberculosis. This case suggests that an abnormal immunological reaction to tuberculosis may be one of the etiological candidates for IgG4-related disease.</abstract><pub>Informa Healthcare</pub><doi>10.3109/s10165-008-0127-z</doi><tpages>4</tpages></addata></record> |
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title | A case of immunoglobulin G4-related chronic sclerosing sialadenitis and dacryoadenitis associated with tuberculosis |
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