Epidural spinal tumor and periaortitis as rare complications of Wegener's granulomatosis

Abstract This case report describes findings in a 61-year-old woman who manifested scleritis, small pulmonary nodules, otitis media, periaortitis, and progressive epidural spinal tumor, associated with elevated serum myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) levels. She was cli...

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Bibliographic Details
Published in:Modern rheumatology 2011-12, Vol.21 (6), p.678-683
Main Authors: Kasagi, Shimpei, Saegusa, Jun, Tsuji, Goh, Sendo, Sho, Miura, Natsuko, Hayashi, Hiroki, Sugimoto, Takeshi, Kawano, Seiji, Nishida, Kotaro, Kakutani, Kenichiro, Morinobu, Akio, Kumagai, Shunichi
Format: Article
Language:English
Subjects:
Epidural Neoplasms - complications
Epidural Neoplasms - pathology
Female
Granulomatosis with Polyangiitis - complications
Granulomatosis with Polyangiitis - pathology
Humans
Inflammation - pathology
Middle Aged
Retroperitoneal Fibrosis - complications
Retroperitoneal Fibrosis - pathology
Thoracic Vertebrae
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Summary:Abstract This case report describes findings in a 61-year-old woman who manifested scleritis, small pulmonary nodules, otitis media, periaortitis, and progressive epidural spinal tumor, associated with elevated serum myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) levels. She was clinically diagnosed with Wegener's granulomatosis, although vasculitis was not diagnosed due to the lack of typical histological findings. We discuss the differential diagnosis in this patient, and the association of MPO-ANCA with periaortitis or epidural spinal tumor.
ISSN:1439-7595
1439-7609
DOI:10.3109/s10165-011-0456-1