CELLULAR ALTERATIONS OF THE ORAL MUCOSA DUE TO ORTHODONTIC APPLIANCES AND TOBACCO SMOKING: A CYTOMORPHOMETRIC STUDY

Introduction: Fixed orthodontic treatment causes chronic low grade irritation on the oral mucosa. Tobacco smoking is considered to be a risk factor in the development of oral cancer. This study was designed to do a cytomorphometric analysis on the buccal mucosal cells in patients undergoing fixed or...

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Bibliographic Details
Published in:Journal of College of Medical Sciences-Nepal 2018-03, Vol.14 (2)
Main Authors: Marla, Vinay, Singh, Varun Pratap, Baral, Dharanidhar, Pokharel, Prabhat Ranjan, Shrestha, Ashish, Gyawali, Rajesh, Giri, Jamal
Format: Article
Language:English
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Summary:Introduction: Fixed orthodontic treatment causes chronic low grade irritation on the oral mucosa. Tobacco smoking is considered to be a risk factor in the development of oral cancer. This study was designed to do a cytomorphometric analysis on the buccal mucosal cells in patients undergoing fixed orthodontic treatment who are tobacco smokers.Methods: Exfoliated buccal mucosal cells were obtained from orthodontic patients (smokers & non-smokers) as well as smokers and non-smokers who are not undergoing any orthodontic treatment. Smears were stained with rapid PAP stain and digital images of 50 cells were analysed using the Image J software.Results and conclusion: Statistical analysis revealed that there were significant increase in the values of nuclear and cell diameter between non-smokers undergoing orthodontic treatment and smokers (p
ISSN:2091-0657
2091-0673
DOI:10.3126/jcmsn.v14i2.18755