Synthesis and characterization of new iminopyridazine butyronitrile hydrobromides

In this study, general methods were applied for the preparation of new iminopyridazine butyronitriles. A series of six new 4-(3-aryl-1,6-dihydro-6-iminopyridazin-1-yl)butyronitrile hydro-bromides (2a-2f) (Scheme 1) have been prepared starting from commercially available 3-amino-6-chloropyridazine in...

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Bibliographic Details
Published in:Journal of Bangladesh Academy of Sciences 2021-01, Vol.44 (2), p.131-138
Main Authors: Rahman, Mohammad Mostafizur, Islam, Md Din, Islam, Zakia, Kumar, Samiron, Chowdhury, Tahmina Akter, Nishino, Hiroshi, Haque, Md Aminul
Format: Article
Language:eng ; jpn
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Summary:In this study, general methods were applied for the preparation of new iminopyridazine butyronitriles. A series of six new 4-(3-aryl-1,6-dihydro-6-iminopyridazin-1-yl)butyronitrile hydro-bromides (2a-2f) (Scheme 1) have been prepared starting from commercially available 3-amino-6-chloropyridazine in two steps with good yields. The synthesized compound’s structures were characterized by IR, 1H NMR and high-resolution mass structures spectral (HRMS) data. Journal of Bangladesh Academy of Sciences, Vol. 44, No. 2, 131-138, 2020
ISSN:0378-8121
2224-7270
DOI:10.3329/jbas.v44i2.51457