Effect of dietary acidification on kidney damage induced in immature chickens by excess calcium and infectious bronchitis virus

Experiments were designed to evaluate the effect of dietary acidification on the development of kidney lesions induced by excess dietary calcium (Ca) and Gray strain infectious bronchitis virus (IBV). Specific pathogen-free (SPF) chicks and SPF chicks inoculated with Gray strain IBV were fed one of...

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Bibliographic Details
Published in:Poultry science 1987-04, Vol.66 (4), p.626-633
Main Authors: Wideman, R.F. Jr, Cowen, B.S
Format: Article
Language:English
Subjects:
ACIDIFICACION
ACIDIFICATION
Acidosis - chemically induced
Acidosis - complications
Acidosis - veterinary
AMMONIUM CHLORIDE
Ammonium Chloride - adverse effects
Animals
CALCIO
CALCIUM
Calcium, Dietary - adverse effects
CHICKENS
Chickens - metabolism
CHLORURE D'AMMONIUM
CLORURO DE AMONIO
CORONAVIRIDAE
Coronaviridae Infections - complications
Coronaviridae Infections - veterinary
DIET
DIETA
ENFERMEDADES (TRACTO URINARIO)
Female
HERIDAS
HORMONAS
HORMONE
HORMONES
Infectious bronchitis virus
Kidney - pathology
MALADIE DE L'APPAREIL URINAIRE
Male
PLAIE
POLLO
POULET
Poultry Diseases - etiology
Poultry Diseases - metabolism
Poultry Diseases - microbiology
REGIME ALIMENTAIRE
Urinary Calculi - etiology
Urinary Calculi - veterinary
URINARY TRACT DISEASES
WOUNDS
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Summary:Experiments were designed to evaluate the effect of dietary acidification on the development of kidney lesions induced by excess dietary calcium (Ca) and Gray strain infectious bronchitis virus (IBV). Specific pathogen-free (SPF) chicks and SPF chicks inoculated with Gray strain IBV were fed one of three diets: a commercial pullet grower ration (1% Ca); a commercial layer ration (3.25% Ca); or layer ration plus .5% ammonium chloride (acidified layer ration). Gray strain IBV significantly reduced total kidney weights in males, reduced total kidney weight as a percentage of body weight in males, increased the number of gross kidney lesions, and decreased the number of filtering nephrons when compared with uninoculated birds when both groups were fed the grower ration. The layer ration induced a 60% incidence of kidney lesions, caused a significant increase in kidney weight asymmetry ratios, and caused a 25% reduction in the number of filtering nephrons. Acidifying the layer ration significantly reduced the incidence of gross kidney lesions and reduced kidney weight asymmetry ratios, but did not prevent Ca-induced reductions in filtering nephrons.
ISSN:0032-5791
1525-3171
DOI:10.3382/ps.0660626