Prevention of coccidiosis in the chukar partridge (Alectoris chukar) by medication with sulfadimethoxine and ormetoprim (Rofenaid)

Rofenaid (a 5:3 mixture of sulfadimethoxine and ormetoprim) was effective in preventing coccidiosis of chukar partridges. Levels of .0100 or .0125% sulfadimethoxine, with the corresponding level of ormetoprim in the ration, gave the best results. These levels markedly reduced mortality in severe inf...

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Bibliographic Details
Published in:Poultry science 1990-10, Vol.69 (10), p.1675-1680
Main Authors: Ruff, M.D. (Protozoan Diseases Laboratory, Livestock and Poultry Sciences Institute, USDA, ARS, Beltsville, MD), Wilkins, G.C
Format: Article
Language:English
Subjects:
Animal Feed
Animals
Anti-Infective Agents - adverse effects
Anti-Infective Agents - therapeutic use
ANTIPROTOZOAIRE
ANTIPROTOZOAL AGENTS
Body Weight - drug effects
COCCIDIOSE
COCCIDIOSIS
Coccidiosis - prevention & control
Coccidiosis - veterinary
CONTROL DE ENFERMEDADES
CONTROLE DE MALADIES
DISEASE CONTROL
DOSAGE
Drug Combinations
EIMERIA
EIMERIA KOFOIDI
EIMERIA LEGIONENSIS
GAIN DE POIDS
GANANCIA DE PESO
MEDICAMENTOS CONTRA PROTOZOARIOS
MORTALIDAD
MORTALITE
MORTALITY
PARTRIDGES
PERDIZ
PERDRIX
Poultry
Poultry Diseases - prevention & control
PREVENTIVE MEDICINE
Pyrimidines - adverse effects
Pyrimidines - therapeutic use
SAFETY
SECURITE
SEGURIDAD
Sulfadimethoxine - adverse effects
Sulfadimethoxine - therapeutic use
SULFAMIDE
SULFONAMIDAS
SULPHONAMIDES
WEIGHT GAIN
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Description
Summary:Rofenaid (a 5:3 mixture of sulfadimethoxine and ormetoprim) was effective in preventing coccidiosis of chukar partridges. Levels of .0100 or .0125% sulfadimethoxine, with the corresponding level of ormetoprim in the ration, gave the best results. These levels markedly reduced mortality in severe infections (over 75% mortality in unmedicated chukars) and eliminated mortality in medicated groups when infections produced 52% mortality or less in unmedicated controls. In the latter infections, Rofenaid also protected against the depression in weight gain seen 6 days postinoculation in unmedicated chukars. Studies in uninoculated chukars showed that Rofenaid has a wide safety margin and did not produce adverse effects even at levels of .0300% sulfadimethoxine. Rofenaid should, therefore, be an effective medication for the prevention of coccidiosis in chukars in the field. Data from the present studies are being submitted to the IR-4 Program of the Food and Drug Administration for consideration of approval for the use of Rofenaid in chukar partridges.
ISSN:0032-5791
1525-3171
DOI:10.3382/ps.0691675