Association of Retinal Nerve Fiber Layer (RNFL) Thickness with Smoking Using Optical Coherence Tomography (OCT) in Pakistani Population

Background: Smoking has multisystem effects on human body due to hypoxia and systemic inflammation, which it produces. This contributory effect is observed in ocular tissues as well. The aim of the study was to evaluate retinal nerve fiber layer (RNFL) thickness in healthy individuals with a history o...

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Bibliographic Details
Published in:Pakistan Journal of Medicine and Dentistry 2024-05, Vol.9 (4)
Main Authors: Sahrish Mukhtar, Sadaf Shaheen, Nadia Yonus, Asma Basharat, Iffat Raza, Mahrukh Kamran
Format: Article
Language:English
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Summary:Background: Smoking has multisystem effects on human body due to hypoxia and systemic inflammation, which it produces. This contributory effect is observed in ocular tissues as well. The aim of the study was to evaluate retinal nerve fiber layer (RNFL) thickness in healthy individuals with a history of smoking, using optical coherence tomography (OCT). Methods: Patients healthy eyes n=300 were examined. Two groups were made; Group A with history of smoking (n=50) and Group B with no history of smoking (n=250). Subjects with a history of diabetes, hypertension, raised intra ocular pressure (IOP >21 mmHg), any neurological disease or family history of glaucoma were excluded from the study. Independent t-test was used to assess the thickness variation with smoking status. ANOVA was used to analyze the differences in both groups. p value
ISSN:2313-7371
2308-2593
DOI:10.36283/PJMD9-4/006