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Post COVID-19 Disseminated Mucormycosis in a 55-year-old patient in Western Amazon: Case report

A feared fungal disease surprised and became a warning to severe cases of COVID-19, especially to health professionals involved with the pandemic. Designated as black fungus for public health services in India, where reported data reflects an increase of more than eighty times the expected increase...

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Published in:Revista brasileira de crescimento e desenvolvimento humano 2022-06, Vol.32 (2), p.351-356
Main Authors: Afonso Viana Macedo Neves, Sebastião, Liadja Souza Silva, Lidyane, Antunes Patzina, Rosely, Cilento Ponce, Cesar, Souza Cordeiro, Jordy, Oliveira de Araújo, Aline, Lepka de Lima, Evelyn, Souza de Matos, Irenilce, José Duailibe Furtado, Juvencio, Varize Pussi, Letícia, Aragão Cavalcante, Erine, Vinícius da Silva, Marcos
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container_title Revista brasileira de crescimento e desenvolvimento humano
container_volume 32
creator Afonso Viana Macedo Neves, Sebastião
Liadja Souza Silva, Lidyane
Antunes Patzina, Rosely
Cilento Ponce, Cesar
Souza Cordeiro, Jordy
Oliveira de Araújo, Aline
Lepka de Lima, Evelyn
Souza de Matos, Irenilce
José Duailibe Furtado, Juvencio
Varize Pussi, Letícia
Aragão Cavalcante, Erine
Vinícius da Silva, Marcos
description A feared fungal disease surprised and became a warning to severe cases of COVID-19, especially to health professionals involved with the pandemic. Designated as black fungus for public health services in India, where reported data reflects an increase of more than eighty times the expected increase for Rhizopus among the communities. The disease has become even more worrisome due to the high mortality already established as an opportunistic infection, coupled with the reserved prognosis for all those infected and hospitalised by the SARS-CoV-2 severity criteria. This patient, who was submitted to corticosteroid therapy, in an excessive dose, therefore immunosuppressive, developed a severe, disseminated clinical form. It was verified the progression of the lesions and thus the high risk of trans- surgical lethality, or, also, by the insufficiency of conduct in removing the lesions to their satisfaction. Thus, the therapeutic option is the associated use of micafungin, liposomal amphotericin B and isavuconazole for the regressive phase. The patient remains hospitalised with progressive and discrete improvement. Until the opportunity of reevaluation of the surgery by the interspecialty collaboration. Uma temida doença fúngica surpreendeu e se tornou um alerta para casos graves de COVID-19, principalmente aos profissionais de saúde envolvidos com a pandemia. Designado como fungo preto para serviços de saúde pública na Índia, onde os dados relatados refletem um aumento de mais de oitenta vezes o aumento esperado para Rhizopus entre as comunidades. A doença tornou-se ainda mais preocupante devido à alta mortalidade já estabelecida como infecção oportunista, aliada ao prognóstico reservado para todos os infectados e internados pelos critérios de gravidade do SARS-CoV-2. Esse paciente, que foi submetido à corticoterapia, em dose excessiva, portanto imunossupressora, desenvolveu uma forma clínica grave e disseminada. Verificou-se a progressão das lesões e, portanto, o alto risco de letalidade transcirúrgica, ou, ainda, pela insuficiência de conduta na remoção das lesões a contento. Assim, a opção terapêutica é o uso associado de micafungina, anfotericina B lipossomal e isavuconazol para a fase regressiva. O paciente permanece internado com melhora progressiva e discreta. Até a oportunidade de reavaliação da cirurgia pela colaboração interespecialista.
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title Post COVID-19 Disseminated Mucormycosis in a 55-year-old patient in Western Amazon: Case report
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