Novel monoclonal antibodies against pancreatic juice from pancreatic cancer patients and their possible application in differential diagnosis

Pancreatic cancer (PC) has a poor clinical prognosis with a 250 kDa and at ~70 kDa, respectively. We propose that investigation of pancreatic juice samples with these mAbs may enable us to perform reliable differential diagnosis of benign and malignant diseases. Furthermore, we demonstrated that sub...

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Bibliographic Details
Published in:International journal of molecular medicine 2011-10, Vol.28 (4), p.599-603
Main Authors: Hamabashiri, Masato, Daichou, Aya, Yasumoto, Makiko, Ogasawara, Sachiko, Nishinakagawa, Takuya, Enjoji, Munechika, Ohshima, Kouichi, Yano, Hirohisa, Nakashima, Manabu
Format: Article
Language:English
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Summary:Pancreatic cancer (PC) has a poor clinical prognosis with a 250 kDa and at ~70 kDa, respectively. We propose that investigation of pancreatic juice samples with these mAbs may enable us to perform reliable differential diagnosis of benign and malignant diseases. Furthermore, we demonstrated that subtractive immunization is a useful method for producing mAbs specific for the pancreatic juice from PC patients.
ISSN:1107-3756
1791-244X
DOI:10.3892/ijmm.2011.717