Microwave-assisted synthesis of novel 8-chloro-[1,2,4]triazolo[4,3-$a$]pyridine derivatives

A series of novel 1,2,4-triazolo[4,3-$a$]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by $^{1}$H NMR, MS, and elemental analysis. This method prov...

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Bibliographic Details
Published in:Turkish journal of chemistry 2015-01, Vol.39, p.867-873
Main Authors: ZHANG, LINJIONG, YANG, MINGYAN, HU, BEIZHEN, SUN, ZHAOHUI, LIU, XINGHAI, WENG, JIANQUAN, TAN, CHENGXIA
Format: Article
Language:English
Subjects:
1, 2, 4-Triazolo[4, 3-$a$]pyridine, urea, microwave-assisted synthesis
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Summary:A series of novel 1,2,4-triazolo[4,3-$a$]pyridine derivatives were synthesized from 2,3-dichloropyridine and hydrazine hydrate as starting materials by multistep reactions under microwave assistance, and their structures were characterized by $^{1}$H NMR, MS, and elemental analysis. This method provides several advantages such as high yields, facile work-up, and environmental friendliness.
ISSN:1300-0527
1303-6130
1303-6130
DOI:10.3906/kim-1408-78