An automatable device for high content chemotaxis assays in the presence of a stable gradient (144.13)

Current approaches to study chemotaxis are limited by gradient instability, low throughput, cumbersome manual manipulations, high cell number requirements, inability to acquire high-content data, and/or poor data quality and reproducibility. We present here a new microfluidics-based approach to stud...

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Bibliographic Details
Published in:The Journal of immunology (1950) 2010-04, Vol.184 (1_Supplement), p.144-144.13
Main Authors: Vu, Elizabeth, Meyvantsson, Ivar, Worzella, Tracy, Skoien, Allyson, Echeverria, Victoria, Lamers, Casey, Echeverria, Daniella, Hayes, Steve
Format: Article
Language:English
Online Access:Get full text
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Summary:Current approaches to study chemotaxis are limited by gradient instability, low throughput, cumbersome manual manipulations, high cell number requirements, inability to acquire high-content data, and/or poor data quality and reproducibility. We present here a new microfluidics-based approach to study leukocyte chemotaxis. The device features strong miniaturization of the use of cells (
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.184.Supp.144.13