Vaccine-Elicited T cells are Important for Intravenous BCG Mediated Protection in a Rhesus macaque Model of Tuberculosis

Our laboratories have shown that intravenous (IV) vaccination with Bacille Calmette-Guerin (BCG; 5×107 CFU) provides robust protection against low-dose Mycobacterium tuberculosis (Mtb) infection in rhesus macaques (9/10 protected [

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Bibliographic Details
Published in:The Journal of immunology (1950) 2020-05, Vol.204 (1_Supplement), p.168-168.4
Main Authors: Zeppa, Joseph John, Darrah, Patricia A, Sutton, Matthew, Pokkali, Supriya, Scanga, Chuck A, Maiello, Pauline, Lin, Philana L, Roederer, Mario, Seder, Robert A, Flynn, JoAnne L
Format: Article
Language:English
Online Access:Get full text
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Description
Summary:Our laboratories have shown that intravenous (IV) vaccination with Bacille Calmette-Guerin (BCG; 5×107 CFU) provides robust protection against low-dose Mycobacterium tuberculosis (Mtb) infection in rhesus macaques (9/10 protected [
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.204.Supp.168.4