Assessing Bone Mineral Density in Sickle Cell Disease Patients and linking it to Admission Rates: A Prospective Uni-center Study

INTRODUCTION: Sickle cell disease (SCD) is an inherited autosomal recessive disorder with bone mineral density (BMD) as a common clinical manifestation of SCD. With a prevalence of 2.6%, Saudi Arabia is among the highest incidence of SCD worldwide. The purpose of this research was to examine how SCD...

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Published in:Journal of Applied Hematology 2024-01, Vol.15 (1), p.69-75
Main Authors: Al-Ansari, Rehab Yusuf, Alshammari, Amal Shilash, Woodman, Alexander, Tawfiq, Sama Khalid, Aldawish, Majed Mutlaq, Banjar, Asem Osama, Fadoul, Tawasoul, Algarni, Mushref Ali, Alorf, Ali Mohammed, Motabgani, Sameerah Mohammedakram, Habib, Ahmad Abdullah
Format: Article
Language:English
Subjects:
bone mineral density
dxa scan
hydroxyurea
osteopenia
osteoporosis
sickle cell disease
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Summary:INTRODUCTION: Sickle cell disease (SCD) is an inherited autosomal recessive disorder with bone mineral density (BMD) as a common clinical manifestation of SCD. With a prevalence of 2.6%, Saudi Arabia is among the highest incidence of SCD worldwide. The purpose of this research was to examine how SCD evolves and how it affects bone density in Saudi patients from an Eastern Province tertiary hospital. METHODS: This was an observational prospective study conducted in the tertiary care hospital among 119 SCD patients. Patients were divided into two groups: Group A – severe SCD patients requiring hospital care ≥3/year; and Group B included patients with a smooth course of SCD who did not require frequent hospitalization (
ISSN:1658-5127
2454-6976
DOI:10.4103/joah.joah_22_24