Impact of Drug Price Regulation on Patient Access to Medicines: A Systematic Review

• Published in: Matrix science pharma 2023-10, Vol.7 (4), p.112-118
• Main Authors: Ashiwaju, Bankole Ibrahim, Orikpete, Ochuko Felix, Alade, Elesho Yusuf, Raji, Ahmed, Adesanya, Abel Olusegun, Nwankwo, Tochukwu Chinwuba
• Format: Article
• Language: English
• ISSN: 2521-0815; 2521-0432
• DOI: 10.4103/mtsp.mtsp_23_23

This systematic review explored the multifaceted impact of drug price regulation on patient access to essential medicines. Recognizing the complexity of this relationship, the paper investigates the influence of various types of drug price regulation mechanisms, the disparities across different geographical regions and health-care systems, and the differential effects between branded and generic drugs. Our findings illustrate that the effects of drug price regulation are not universally uniform or predictable, but rather, they are highly context dependent. Direct price control measures can, on the one hand, improve accessibility through affordability; yet on the other hand, potentially disrupt drug supply. Indirect price control methods, such as reference pricing and value-based pricing, while designed to spur competition, can be hampered by administrative complexities and potentially stifle pharmaceutical innovation. Despite the pervasive use of drug price regulation, access to essential medicines remains disparate and inequitable, indicating a need for a comprehensive approach that includes health system reforms, improved health literacy, and greater collaboration between stakeholders. Future research should further investigate the enduring disparities in patient access to medicines, the long-term effects of various pricing mechanisms, and their interplay with the evolving pharmaceutical industry and health-care landscapes.