Emerging technologies for biotherapeutic bioanalysis from a high-throughput and multiplexing perspective: insights from an AAPS emerging technology action program committee

This manuscript aims to provide insights and updates on emerging technologies from a throughput and multiplexing perspective and to update readers on changes in previously reported technologies. The technologies discussed range from nascent (ultrasensitive Cira, Intellicyt , Dynaxi and Captsure™) to...

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Bibliographic Details
Published in:Bioanalysis 2018-02, Vol.10 (3), p.181-194
Main Authors: Purushothama, Shobha, Dysinger, Mark, Chen, Yao, Österlund, Karolina, Mora, Johanna, Chunyk, Allison Given, Peloquin, Russ
Format: Article
Language:English
Subjects:
Captsure
Dynaxi
Ella
emerging technology
Intellicyt
microfluidic
multianalyte detection
multiplexing
SQIDLite
throughput
ultrasensitive Cira
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Summary:This manuscript aims to provide insights and updates on emerging technologies from a throughput and multiplexing perspective and to update readers on changes in previously reported technologies. The technologies discussed range from nascent (ultrasensitive Cira, Intellicyt , Dynaxi and Captsure™) to the more established (Ella and SQIDlite™). For the nascent technologies, there was an emphasis on user interviews and reviews, where available, to help provide an unbiased view to our readers. For the Ella, a review of published user data as well as author and other user experiences are summarized. Due to their emergent nature, all the technologies described are applicable in the early drug development stage, may require an upfront investment of capital and may not perform as expected.
ISSN:1757-6180
1757-6199
DOI:10.4155/bio-2017-0196