Photonic nanoparticles: emerging theranostics in cancer treatment

• Published in: Therapeutic delivery 2023-04, Vol.14 (4), p.311-329
• Main Authors: Shahcheraghi, Seyed Hossein, Shahcheraghi, Seyed Hadi, Lotfi, Marzieh, Lotfi, Malihe, Khaleghinejad, Seyed Hossein, Tambuwala, Zara M, Mishra, Vijay, Mishra, Yachana, Serrano-Aroca, Ángel, A Aljabali, Alaa A, El-Tanani, Mohamed, Naikoo, Gowhar A, Chava, Sai Raghuveer, Charbe, Nitin B, Bharti, Shivani, Jaganathan, Saravana Kumar, Goyal, Rohit, Negi, Poonam, Tambuwala, Murtaza M, Folorunso, Oladipo
• Format: Article
• Language: English
• Subjects: gold; hybrids; iron; nanoparticles; photonics; polymer; silver
• ISSN: 2041-5990; 2041-6008
• DOI: 10.4155/tde-2023-0011

This review explores the potential of photonic nanoparticles for cancer theranostics. Photonic nanoparticles offer unique properties and photonics capabilities that make them promising materials for cancer treatment, particularly in the presence of near-infrared light. However, the size of the particles is crucial to their absorption of near-infrared light and therapeutic potential. The limitations and challenges associated with the clinical use of photonic nanoparticles, such as toxicity, immune system clearance, and targeted delivery to the tumor are also discussed. Researchers are investigating strategies such as surface modification, biodegradable nanoparticles, and targeting strategies to improve biocompatibility and accumulation in the tumor. Ongoing research suggests that photonic nanoparticles have potential for cancer theranostics, further investigation and development are necessary for clinical use. Tiny particles called ‘photonic nanoparticles’ can be used to help treat cancer. These particles have special properties that allow them to be used with special light to treat cancer. However, the size of the particles is really important, so scientists are trying to find ways to make sure they are the right size. There are also some challenges with using these particles in people, like making sure they don't harm the body and that they go to the right place. Scientists are working on ways to improve the safety of these particles and make sure they go where they need to. Photonic nanoparticles show promise for cancer theranostics, but challenges remain. Researchers are exploring strategies such as surface modification and targeting to improve biocompatibility and accumulation in tumors. Further investigation and development are necessary for clinical use. #nanoparticles #cancertheranostics