Synthesis of Iron Oxide Magnetic Nanoparticles: Characterization and its Biomedical Application

• Published in: Journal of Applied Sciences and Environmental Management 2022-05, Vol.26 (2), p.287-295
• Main Authors: Usha, V., Amutha, E., Pushpalaksmi, E., Samraj, Jenson J., Rajaduraipandian, S., Gandhimathi, S., Annadurai, G.
• Format: Article
• Language: English
• ISSN: 1119-8362; 2659-1502; 2659-1502; 2659-1499
• DOI: 10.4314/jasem.v26i2.16

In the present time, Iron oxide magnetic nanoparticles (IOMNPs) have paid considerable attention due to their exclusive applications in terms of surface-to-volume ratio, superparamagnetism, high surface area, biosensor, bio-separation, catalysis, and biomedicine. Our goal was to synthesis iron oxide magnetic nanoparticles by chemical route technique. The preparation method had a very large effect on the size, shape, and surface chemistry of the magnetic nanoparticles including their applications. The iron chloride solution was prepared by mixing deionized water with iron chloride tetrahydrate. The synthesized powder was characterized by XRD, UV-vis, SEM, FT-IR, DLS, FL, and TGA techniques. Moreover, antibacterial activity was evaluated using the synthesized IOMNPs against Escherichia coli (A), Pseudomonas (B), Enterobacter (C), Staphylococcus aureus (D), and Bacillus subtilis (E) in the concentration of 0.1 mg and 0.5 mg. The results showed that Bacillus subtilis possess a higher antibacterial activity at the concentration of 0.5 mg comparing the other bacterial species. The outcome of this work would contribute to the present understanding of the biomedical application with the obtained size, shape, and synthesized method.