Evaluation of Serum Anticardiolipin Antibodies and D-dimer in Recipients of COVID-19 Vaccines in Ado-Ekiti, Ekiti State, Nigeria

Coronavirus disease 2019 (COVID-19) manifests itself in a variety of ways, implying a wide range of host autoimmune responses which could lead to disseminated intravascular coagulation. This study was designed to evaluate serum anticardiolipin antibodies and D-dimer in recipients of COVID 19 vaccine...

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Bibliographic Details
Published in:Journal of Applied Sciences and Environmental Management 2023-11, Vol.27 (11), p.2495-2501
Main Authors: Odewusi, O. O., Dodo, J. J., Omotayo, F. E., Obadire, S. O., Omon, E. A., Oguntuase, M. O., Alake, O. A.
Format: Article
Language:English
Subjects:
Anticardiolipin
COVID-19
Vaccine
Recipient
Respiratory infection
Online Access:Get full text
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Summary:Coronavirus disease 2019 (COVID-19) manifests itself in a variety of ways, implying a wide range of host autoimmune responses which could lead to disseminated intravascular coagulation. This study was designed to evaluate serum anticardiolipin antibodies and D-dimer in recipients of COVID 19 vaccines in Ado-Ekiti, Ekiti State, Nigeria. The study population comprised sixteen (16) fully vaccinated subjects, fifteen (15) partially vaccinated subjects and fifteen (15) unvaccinated subjects (control). Anticardiolipin antibodies and D-dimer were analyzed using ELISA. D-dimer and anticardiolipin antibodies were significantly higher in fully and partially vaccinated subjects compared to control (p0.05). Anticardiolipin and D-dimer were significantly higher in recipients of mRNA vaccines compared to viral vector vaccines (p
ISSN:1119-8362
2659-1502
2659-1502
2659-1499
DOI:10.4314/jasem.v27i11.19