Acute effects of moderate-intensity constant training on circulatory fibroblast growth factor 21, resis-tin, and adiponectin of physically inactive young adults

• Published in: Retos (Madrid) 2024-06, Vol.55, p.379-385
• Main Authors: Carrasco-Molina, Jeremías, Iuspa-Santelices, Giannina, Flores-Ojeda, Francisca, Ruíz-Uribe, Matías, Martínez-Huenchullán, Sergio Francisco
• Format: Article
• Language: English
• Subjects: Cytokines; Endurance training; Exercise; Metabolic syndrome; Sedentary behavior
• ISSN: 1579-1726; 1988-2041
• DOI: 10.47197/retos.v55.103732

Introduction: physical inactivity affects metabolic health, and it has been described that physical exercise is able to counter these disturbances. Fibroblast growth factor (FGF) 21, resistin, and adiponectin are known cytokines that are sensitive to physical inactivity and exercise, however, their acute behaviour after one session of exercise in physically inactive young adults is unclear. Therefore, this study aimed to investigate the effects of a session of moderate-intensity continuous training (MICT) on the circulatory levels of FGF21, resistin, and adiponectin of physically inactive young adults. Material and methods: quasi-experimental study, where 20 physically inactive young adults, with body mass indexes between 18 and 30 kg/m2 were included. All performed one MICT session, with an intensity of 60% of their heart rate reserve on a treadmill for 30 minutes. Anthropometric measurements were evaluated (weight, height, waist and hip circumferences, lean and fat mass) prior to exercise, and venous blood samples were taken before and after exercise, where glycemia, insulin, lipid profiles, transaminases, FGF21, resistin, and adiponectin were assessed. Results: one MICT session decreased the circulatory levels of insulin (median 23.5 vs 10.9 µUI/ml; p