Multiple Right and Left Pulmonary Arteries and Subdivisions of Inferior Mesenteric Artery Aneurysms in Behcet's Disease Case: A Rare Clinical Presentation

Behcet's disease is a multi-systemic inflammatory disorder with cutaneous acneiform eruptions, orogenital aphthae, uveitis, arthritis and systemic vascular inflammation. One of the rare vascular manifestations is thoraco-abdominal aortic and pulmonary aneurysm that is associated with high risk...

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Bibliographic Details
Published in:Oman medical journal 2014-05, Vol.29 (3), p.1-3
Main Authors: Zandkarimi , Mohammad Reza, Faridhosseini , Reza, Jabbari , Farah, Shirkani , Afshin, Yousefzadeh , Hadis, Sahebari , Maryam, Basiri , Reza
Format: Article
Language:English
Subjects:
AUTOIMMUNITY
BEHCIT'S DISEASE
CARDIOVASCULAR DISEASES
Case Report
PATIENTS
PULMONARY ARTERIES
THERAPY
أمراض القلب و الأوعية الدموية
الشرايين الرئوية
العلاج
المرضى
المناعة الذاتية
داء بهجت
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Summary:Behcet's disease is a multi-systemic inflammatory disorder with cutaneous acneiform eruptions, orogenital aphthae, uveitis, arthritis and systemic vascular inflammation. One of the rare vascular manifestations is thoraco-abdominal aortic and pulmonary aneurysm that is associated with high risk of morbidity and mortality. We report a 36-year-old man with chronic cough, hemoptysis, significant weight loss, and orogenital ulcers from one year before referral. Initial assessments revealed multiple parahillar nodules in chest X-ray, chronic inflammatory anemia, erythrocyte sedimentation rate more than 100, and positive Human Leukocyte Antigen B5 and B51. Evaluation for infection and malignancies was unremarkable. Open exploratory lung study showed multiple pulsatile nodules in both lungs. AMIGO computed tomogram confirmed multiple right and left pulmonary artery aneurysms and impending to rupture aneurysm at subdivision of inferior mesenteric artery. After beginning of three methylprednisolone and cyclophosphamide pulse doses, the clinical aspect of the patient dramatically improved. Although pulmonary aneurysm is a rare manifestation of Behcet's disease and it is more infrequent in the distal branches, it can be seen in patients presenting with inflammatory disease and respiratory manifestations and with Behcet's disease diagnosis. Corticosteroid pulse-therapy could be considered as the first line of medical treatment in these patients.
ISSN:1999-768X
2070-5204
DOI:10.5001/omj.2014.63