Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan

• Published in: Pakistan Armed Forces medical journal 2022-06, Vol.72 (SUPPL-2), p.S208-11
• Main Authors: Khan, Muhammad Ijaz, Haider, Ghulam, Ahmed, Khalil, Shaikh, Shiraz, Abbas, Kiran, Ahmed, Moiz, Sohail, Hamza
• Format: Article
• Language: English
• ISSN: 0030-9648; 2411-8842
• DOI: 10.51253/pafmj.v72iSUPPL-2.3996

Objectives: To evaluate the tumor grades in different receptors (Estrogen, Progesterone and Her-2/neu) categories and age groups among women with Breast Cancer. Study Design: An observational cross-sectional study. Place and Duration of Study: Oncology department, Jinnah Postgraduate Medical Center, Karachi, from Jul 2017 to Dec 2018. Methodology: Total of 450 patients were enrolled in this study using non-probability consecutive sampling technique. The Receptors Status of Estrogen, Progesterone and Her2/neu was resolved into 4 different categories as i) Triple Positive (ER+PR+HER2+), ii) Triple Negative (ER-PR-HER2-), iii) ER+PR+Her2-, iv) ER–PR-Her2+. Age-wise, patients were divided into 3 groups. Results: The mean age of patients was 46.57 years ± 10.82. No patient was observed with Grade I tumor while 240 with Grade II and 210 with Grade-III. 164/450 patients were observed in the ER+PR+Her2- category. Out of 164, 68.3% were Grade-II and 31.7% were Grade-III (p˂0.001). In Triple-Negative category, 94 patients were observed, 31.90% were Grade-II while 68.10% were Grade-III (p