Pupil Response to Tropicamide following Corneal Crosslinking

Purpose To evaluate the effect of corneal crosslinking (CXL) with ultraviolet A (UVA) irradiation on pupil response to tropicamide 0.5% instillation. Methods This prospective interventional study enrolled 17 patients (19 eyes) with progressive keratoconus who underwent CXL with UVA irradiation. Cent...

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Bibliographic Details
Published in:European journal of ophthalmology 2016-09, Vol.26 (5), p.394-397
Main Authors: Kymionis, George D., Paraskevopoulos, Theodore A., Liakopoulos, Dimitrios A., Grentzelos, Michael A., Kouroupaki, Anna I., Tsoulnaras, Konstantinos I., Panagopoulou, Sophia I., Mazzotta, Cosimo, Detorakis, Efstathios T.
Format: Article
Language:English
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Summary:Purpose To evaluate the effect of corneal crosslinking (CXL) with ultraviolet A (UVA) irradiation on pupil response to tropicamide 0.5% instillation. Methods This prospective interventional study enrolled 17 patients (19 eyes) with progressive keratoconus who underwent CXL with UVA irradiation. Central corneal thickness (CCT) was evaluated with the use of anterior segment optical coherence tomography (Visante OCT 3.0). Pupil diameter was measured with the use of Colvard infrared pupillometer before the instillation of tropicamide 0.5% and after the instillation of tropicamide every 5 minutes for total duration of 30 minutes. Corneal epithelial integrity was examined with the use of fluorescein dye staining. Measurements were performed 1 day preoperatively and 1 month postoperatively, with emphasis on simulating the same light conditions regarding the pupil measurements. Results No intraoperative or postoperative complications were observed in any of the patients. Mean CCT decreased significantly (p
ISSN:1120-6721
1724-6016
DOI:10.5301/ejo.5000758