Real-World Outcomes of Anti-VEGF Treatment for Retinal Vein Occlusion in Portugal

Purpose Retinal vein occlusion (RVO) is an important cause of visual disability in the modern world. We aim to evaluate the real-world outcomes of patients with RVO treated with anti-vascular endothelial growth factor (VEGF) in Portugal. Methods We performed a retrospective, observational, multicent...

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Published in:European journal of ophthalmology 2017-11, Vol.27 (6), p.756-761
Main Authors: Vaz-Pereira, Sara, Marques, Inês P., Matias, João, Mira, Filipe, Ribeiro, Lígia, Flores, Rita
Format: Article
Language:English
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Summary:Purpose Retinal vein occlusion (RVO) is an important cause of visual disability in the modern world. We aim to evaluate the real-world outcomes of patients with RVO treated with anti-vascular endothelial growth factor (VEGF) in Portugal. Methods We performed a retrospective, observational, multicenter study including 8 centers across Portugal and 200 patients treated with either ranibizumab or bevacizumab. Data were collected at 3 time points: time of diagnosis (0 time point) and 6 and 12 months after initiating treatment. Demographic and clinical data were collected. Results Median visual acuity (VA) and central macular thickness (CMT) improved in the branch RVO (BRVO), central RVO (CRVO), bevacizumab, and ranibizumab groups at 6 and 12 months compared to baseline, with CMT improving further only in the CRVO and ranibizumab groups between 6 and 12 months (p = 0.002 and p = 0.001, respectively). The CMT was lower in the ranibizumab group compared to the bevacizumab group both at 6 and 12 months (p
ISSN:1120-6721
1724-6016
DOI:10.5301/ejo.5000943