Synthesis, Spectral Studies Antibacterial and Antifungal Activity of 2"-Amino-4"-[2 -(4'-Chlorophenyl)-6-Methyl Imidazo[1, 2-a]Pyridin-3-yl]-6"-Aryl Nicotinonitrile

Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – amino - 4" - [2 - (4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitr...

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Bibliographic Details
Published in:International letters of chemistry, physics and astronomy physics and astronomy, 2015-04, Vol.49, p.161-166
Main Authors: Bhuva, V.V., Bhadani, V.N., Purohit, H.D., Purohit, Dipak M.
Format: Article
Language:English
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Summary:Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – amino - 4" - [2 - (4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitriles ( 4a-4l ) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50μg/ml. The structures of the products have been elucidated by IR, 1 H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.
ISSN:2299-3843
2299-3843
DOI:10.56431/p-1ap4oq