EFFECT OF RIBOFLAVIN DEFICIENCY ON RAT ELECTRORETINOGRAM

Weanling male rats were fed a 18% casein diet with and without riboflavin. After 6 weeks of feeding, electroretinogram in both riboflavin deficient and control rats were examined. The ratio of amplitude in b wave/a wave was found to decrease in deficient rats. After the rats in the deficient group w...

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Bibliographic Details
Published in:Journal of vitaminology 1966/12/10, Vol.12(4), pp.281-285
Main Authors: KOYANAGI, TATSUO, SONE, KIYOHIDE, SUGIHARA, SHIGETAKA, TAMURA, ATSUHIRO
Format: Article
Language:English
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Summary:Weanling male rats were fed a 18% casein diet with and without riboflavin. After 6 weeks of feeding, electroretinogram in both riboflavin deficient and control rats were examined. The ratio of amplitude in b wave/a wave was found to decrease in deficient rats. After the rats in the deficient group were returned to a normal diet for 4 weeks, the ratio become comparable to that of control rats. Microscopic examination revealed that succinic acid dehydrogenase activity which located densely in the border of outer plexiform and inner granular layers and also in the layer of rods and cones decreased remarkably in deficient rats.
ISSN:0022-5398
DOI:10.5925/jnsv1954.12.281