Photodynamic and Acoustic Therapy: A Breakthrough in Combating Antibiotic-Resistant Bacteria

• Published in: Journal of pioneering medical sciences 2024-07, Vol.13 (4), p.9-18
• Main Author: Sultan, Rania Mohammad Sabri
• Format: Article
• Language: English
• ISSN: 2309-7981; 2309-7981
• DOI: 10.61091/jpms202413402

The emergence and spread of antibiotic-resistant bacteria is a major public health concern worldwide, posing a serious threat to the effectiveness of current antibiotic treatments. To address this issue, there is a growing need to explore alternative methods for controlling antibiotic-resistant pathogens. This study aims to provide a cost-effective and efficient process to reduce multidrug resistance and establish a system to eliminate multidrug-resistant bacteria. The study begins with the isolation of one or more bacteria in an aseptic, closed environment, followed by inoculation into saline. The sample is then exposed to either moderate sound wave at a predetermined frequency and intensity, red light at a predetermined wavelength, or both. The bacteria in the sample are exposed to the sound and red light, which may cause some of the resistant bacteria to become sensitive to antibiotics. The sound and red light are designed to penetrate the DNA of the bacteria, reversing their resistance to sensitivity. This process either promotes bacterial growth, causing them to scatter away from the canter of a petri dish, or kills them completely. In conclusion, When the organisms are exposed to audible sound alone or in combination with red light, colony formation decreases, and the colonies separate from each other, becoming weaker. In some cases, the colonies take on irregular shapes or die off considerably.