DIANEMYCIN, AN ANTIBIOTIC OF THE GROUP AFFECTING ION TRANSPORT

Dianemycin is an antibiotic previously reported to affect cation transport and to be effective in treating coccidiosis in chickens. It is isolated from a fermentation broth of Streptomyces hygroscopicus. The compound was found to be primarily active against gram-positive organisms. The chemical prop...

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Bibliographic Details
Published in:Journal of antibiotics 1969/04/25, Vol.22(4), pp.161-164
Main Authors: HAMILL, R. L., HOENH, M. M., PITTENGER, G. E., CHAMBERLIN, J., GORMAN, M.
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - toxicity
Bacteria - drug effects
Biological Transport - drug effects
Chemical Phenomena
Chemistry, Physical
Chromatography, Paper
Fermentation
Fungi - drug effects
Infrared Rays
Mice
Oxidation-Reduction
Periodic Acid
Spectrum Analysis
Streptomyces
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Summary:Dianemycin is an antibiotic previously reported to affect cation transport and to be effective in treating coccidiosis in chickens. It is isolated from a fermentation broth of Streptomyces hygroscopicus. The compound was found to be primarily active against gram-positive organisms. The chemical properties of dianemycin indicate a close relationship to monensin and other acidic cation complexing compounds.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.22.161