A novel 1beta-methylcarbapenem, J-111,225: effects of the C-3 and C-5 stereochemistry of the pyrrolidinylthio side chain on antibacterial activities

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Bibliographic Details
Published in:Journal of antibiotics 2000, Vol.53 (3), p.314-316
Main Authors: Imamura, H, Shimizu, A, Sato, H, Sugimoto, Y, Sakuraba, S, Nagano, R, Yamada, K, Hashizume, T, Morishima, H
Format: Article
Language:English
Subjects:
Animals
Anti-Bacterial Agents - adverse effects
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Bacteria - drug effects
Carbapenems - adverse effects
Carbapenems - chemistry
Carbapenems - pharmacology
Epilepsy - chemically induced
Microbial Sensitivity Tests
Molecular Conformation
Pyrrolidines - chemistry
Rats
Stereoisomerism
Structure-Activity Relationship
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ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.53.314