HLA antigens and anti-sperm antibody production in Iranian vasectomized men

Dear Editor： Anti-sperm antibodies （ASAs） are composed of numerous antibodies interacting with multiple sperm antigens that play a role in fertility. In males, ASAs cause ＇immune infertility＇ by decreasing sperm counts and normal forms, as well as reducing sperm motility and viability, markedly redu...

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Bibliographic Details
Published in:Journal of biomedical research 2015, Vol.29 (1), p.87-90
Main Authors: Azizi, Gholamreza, Namaki, Saeed, Mirshafiey, Abbas, Hamid, Kabir Magaji
Format: Article
Language:English
Subjects:
LA抗原
伊朗
抗精子抗体
民用航空运输
男性
精子抗原
结扎
输精管
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Summary:Dear Editor： Anti-sperm antibodies （ASAs） are composed of numerous antibodies interacting with multiple sperm antigens that play a role in fertility. In males, ASAs cause ＇immune infertility＇ by decreasing sperm counts and normal forms, as well as reducing sperm motility and viability, markedly reducing the likelihood of natural conception. The development of ASA in the male depends on the release of sequestered antigens on germ cells following the disruption of the blood-testis barrier.
ISSN:1674-8301
DOI:10.7555/JBR.20140113