Influence of acid-etching after grit-blasted on osseointegration of titanium dental implants: in vitro and in vivo studies

• Published in: Journal of materials science. Materials in medicine 2013-08, Vol.24 (8), p.2047-2055
• Main Authors: Herrero-Climent, M., Lázaro, P., Vicente Rios, J., Lluch, S., Marqués, M., Guillem-Martí, J., Gil, F. J.
• Format: Article
• Language: English
• Subjects: Acid Etching, Dental - adverse effects; Acid Etching, Dental - methods; Animals; Assaig de materials; Biological and medical sciences; Biomaterials; Biomedical Engineering and Bioengineering; Biomedical materials; Cells, Cultured; Ceramics; Chemistry and Materials Science; Ciències de la salut; Composites; Dental Implantation, Endosseous - instrumentation; Dental implants; Dental Implants - adverse effects; Dentistry; Enginyeria dels materials; Equipment Failure Analysis; Female; Glass; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics; Humans; Implants dentals; Materials Science; Materials Testing; Maxillofacial surgery. Dental surgery. Orthodontics; Medical sciences; Medicina; Natural Materials; Osseointegrated dental implants; Osseointegration - physiology; Ossos; Osteoblasts - cytology; Osteoblasts - drug effects; Osteoblasts - physiology; Polymer Sciences; Rabbits; Regeneració; Regenerative Medicine/Tissue Engineering; Surface Properties; Surface roughness; Surfaces and Interfaces; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology. Biomaterials. Equipments; Thin Films; Time Factors; Titanium; Titanium - chemistry; Titanium - pharmacology; Transplants & implants; Àrees temàtiques de la UPC
• ISSN: 0957-4530; 0957-4522; 1573-4838
• DOI: 10.1007/s10856-013-4935-0

Rough implant surfaces have shown improved osseointegration rates. In a majority of dental implants, the microrough surfaces are obtained by grit blasting and/or acid-etching. The aim of this contribution was to evaluate the effects of acid-etching, after the grit-blasted treatment in titanium dental implants, on surface wettability, surface energy, osteoblast responses and its osseointegration behavior. Four surfaces were studied: as-machined, acid-etched, micro-rough by grit-blasting and the combination grit-blasted surface with acid-etched. The surfaces with increasing roughness show more osteoblastic adhered cells. This effect was most pronounced on samples blasted and blasted with acid-etching. The roughness obtained by grit-blasting is the main factor in comparison with the acid etching treatment in the biological response. These results were confirmed in vivo tests and histological analysis. The results demonstrated that the combination of the grit-blasted and acid-etched accelerated lightly bone regeneration at the different periods of implantation in comparison with the grit-blasted implants.