HACEK infective endocarditis: characteristics and outcomes from a large, multi-national cohort

The HACEK organisms (Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens, and Kingella species) are rare causes of infective endocarditis (IE). The objective of this study is to describe the clinical characteristics and outcomes of patients with HACEK endocardi...

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Published in:PloS one 2013-05
Main Authors: Chambers, Stephen T, Murdoch, David, Morris, Arthur, Holland, David, Pappas, Paul, Almela, M. (Manel), Fernández Hidalgo, Nuria, Almirante, Benito, Bouza, Emilio, Forno, Davide, Rio, Ana del, Hannan, Margaret M, Harkness, Jonh, Kanafani, Zeinha A, Lalani, Tahaniyat, Lang, Selwyn, Raymond, Nigel, Read, Kerry, Vinogradova, Tatiana, Woods, Christopher W, Wray, Dannah, Corey, G. Ralph, Chu, Vivian H, Sitges Carreño, Marta, Miró Meda, José M, Moreno Camacho, Ma. Asunción, Anguera Camós, Ignasi, International Collaboration on Endocarditis Prospective Cohort Study (ICE-PCS) Investigators
Format: Article
Language:English
Subjects:
Control d'infeccions
Endocarditis
Infection control
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Summary:The HACEK organisms (Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens, and Kingella species) are rare causes of infective endocarditis (IE). The objective of this study is to describe the clinical characteristics and outcomes of patients with HACEK endocarditis (HE) in a large multi-national cohort. Patients hospitalized with definite or possible infective endocarditis by the International Collaboration on Endocarditis Prospective Cohort Study in 64 hospitals from 28 countries were included and characteristics of HE patients compared with IE due to other pathogens. Of 5591 patients enrolled, 77 (1.4%) had HE. HE was associated with a younger age (47 vs. 61 years; p
ISSN:1932-6203
1932-6203