Bat Reservoirs for Rabies Virus and Epidemiology of Rabies in Colombia: a review

• Published in: CES medicina veterinaria y zootecnia 2017, Vol.12 (2), p.134-150
• Main Authors: Cifuentes Jiménez, Jimmy Fernando, Pérez Lopéz, Rubén Darío, Verjan Garcia, Noel
• Format: Article
• Language: English
• Subjects: Animal bites; Bats; Chiroptera; Complementary DNA; Deforestation; Disease; doença zoonótica; enfermedad zoonótica; Epidemiology; genetic variants; Laboratories; Lyssavirus; Rabies; Rhabdoviridae; RNA polymerase; variantes genéticas; VETERINARY SCIENCES; Viruses; Zoonoses; zoonotic diseases
• ISSN: 1900-9607; 1900-9607
• DOI: 10.21615/cesmvz.12.2.5

RABV variants V3 and V4 are the most prevalent in Colombia, and this situation seems to be influenced by increased deforestation and urban architecture that provides shelter, causing more frequent interactions between humans and bats 44 The variant V4, that is associated with frugivorous and insectivorous bats, was isolated from a dog and a human in the northern of Colombia 54 RABV was isolated for the first time from bats in Colombia by Alarcon in 1968, who reported the isolation of two strain of RABV from insectivorous and frugivorous bats (Myotis nigricans, Lasiurus ega and Carollia perspicillata) captured from areas of the departments of Guajira, Santander and Antioquia. FAT can be appLied in fresh or frozen brain tissues sections, with very simiLar resuLts (99.8% sensitivity and 100 % specificity) when appLied to fresh or formaLin-fixed tissues -, however, it shouLd not be used in decomposed tissue sampLes 60 Reverse transcription PCR (RT-PCR) CLassicaL reverse transcription-poLymerase chain reaction assay has been reported to be a sensitive and specific tooL for routine diagnostic purposes 62 It consist of the use of a reverse transcriptase to synthesize a compLementary DNA copy from viraL RNA and then, conventionaL PCR is used to ampLify a gene fragment from the virus genome -. The disease is mainly Linked to felines such as cats that may hunt infected bats, getting infected too, which make a rabid cat that usually contact with humans, transmitting the virus. [...]evaluation of rapid diagnosis techniques such as RT-PCR to detect RABV in bat tissues might be needed to promote active surveillance to bats populations. First edit.