Positive Anti-HIV ELISA Results in Pregnancy: Is It Reliable?

Background: Human immunodeficiency virus (HIV) can be transmitted from mothers to their babies during pregnancy, delivery through vaginal fluids or breastfeeding. As false positivity anti-HIV results due to pregnancy could be detected and no relevant study have been reported in Northern Cyprus so fa...

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Published in:Infectious diseases in obstetrics and gynecology 2022-02, Vol.2022, p.1157793-6
Main Authors: Güler, Emrah, Arıkan, Ayşe, Abobakr, Mariam, Sayan, Murat, Süer, Kaya, Şanlıdağ, Tamer
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Analysis
Anti-Retroviral Agents - therapeutic use
Antiviral agents
Breast feeding
Enzyme-Linked Immunosorbent Assay
Female
HIV
HIV (Viruses)
HIV Infections - diagnosis
HIV Infections - drug therapy
HIV testing
HIV-1 - genetics
Human immunodeficiency virus
Humans
Infants
Infectious Disease Transmission, Vertical
Laboratories
Pregnancy
Pregnancy Complications, Infectious - diagnosis
Pregnancy Complications, Infectious - drug therapy
Pregnant women
RNA
Womens health
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Summary:Background: Human immunodeficiency virus (HIV) can be transmitted from mothers to their babies during pregnancy, delivery through vaginal fluids or breastfeeding. As false positivity anti-HIV results due to pregnancy could be detected and no relevant study have been reported in Northern Cyprus so far, we aimed to estimate the false anti-HIV positivity rate in pregnant women. Methods: A total of 11.977 women admitted to Near East University Hospital between 2015 and 2018 were involved. The fourth generation anti-HIV-1/2 ELISA test was carried out by chemiluminescence enzyme immunoassay. Positive results were confirmed by real-time polymerase chain reaction (rt-PCR). SPSS (Statistical Package for the Social Sciences) Demo Ver 22 program was used for statistical analysis and significance (p
ISSN:1064-7449
1098-0997
1098-0997
DOI:10.1155/2022/1157793