Intravenous thrombolysis with rt-PA in stroke: experience of the moroccan stroke unit

• Published in: The Pan African medical journal 2016, Vol.24 (207), p.207-207
• Main Authors: Chtaou, Naima, Rachdi, Lamyae, Midaoui, Aouatef El, Souirti, Zouhair, Wahlgren, Nils, Belahsen, Mohammed Faouzi
• Format: Article
• Language: English
• Subjects: Administration, Intravenous; Atrial Fibrillation - complications; Brain Ischemia - drug therapy; Brain Ischemia - etiology; Case Series; Female; Fibrinolytic Agents - administration & dosage; Humans; Hypertension - complications; intravenous thrombolysis; Male; Medicin och hälsovetenskap; Middle Aged; Morocco; Risk Factors; rt-pa; stroke; Stroke - drug therapy; Stroke - etiology; Time Factors; Tissue Plasminogen Activator - administration & dosage; Treatment Outcome
• ISSN: 1937-8688; 1937-8688
• DOI: 10.11604/pamj.2016.24.207.8815

The majority of strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage has occurred. We report the case series of all patients who were treated with rt-PA at Stroke Unit of HASSAN II University hospital between 2010 and 2013. There were 52 patients treated with intravenous rtPA during the study period. The mean age was 63 years with the no gender predominance (sex ratio 1.02). Hypertension was the most common vascular risk factor (31%) and 17% of patients suffered from atrial fibrillation. 17 of 52 patients (32.7%) were treated within a 3 hours window of stroke onset and 35 of 52 (67.3%) patients were treated within 3-4.5 h. Twenty five patients (48%) had significant early improvements within 24 hours and twenty one (40.3%) patients had good outcomes at 3 months and fifteen patients (29%) died within the same period.