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Design, Synthesis, and Biomedical Application of Multifunctional Fluorescent Polymer Nanomaterials
Luminescent polymer nanomaterials not only have the characteristics of various types of luminescent functional materials and a wide range of applications, but also have the characteristics of good biocompatibility and easy functionalization of polymer nanomaterials. They are widely used in biomedica...
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Published in: | Molecules (Basel, Switzerland) Switzerland), 2023-04, Vol.28 (9), p.3819 |
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description | Luminescent polymer nanomaterials not only have the characteristics of various types of luminescent functional materials and a wide range of applications, but also have the characteristics of good biocompatibility and easy functionalization of polymer nanomaterials. They are widely used in biomedical fields such as bioimaging, biosensing, and drug delivery. Designing and constructing new controllable synthesis methods for multifunctional fluorescent polymer nanomaterials with good water solubility and excellent biocompatibility is of great significance. Exploring efficient functionalization methods for luminescent materials is still one of the core issues in the design and development of new fluorescent materials. With this in mind, this review first introduces the structures, properties, and synthetic methods regarding fluorescent polymeric nanomaterials. Then, the functionalization strategies of fluorescent polymer nanomaterials are summarized. In addition, the research progress of multifunctional fluorescent polymer nanomaterials for bioimaging is also discussed. Finally, the synthesis, development, and application fields of fluorescent polymeric nanomaterials, as well as the challenges and opportunities of structure-property correlations, are comprehensively summarized and the corresponding perspectives are well illustrated. |
doi_str_mv | 10.3390/molecules28093819 |
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They are widely used in biomedical fields such as bioimaging, biosensing, and drug delivery. Designing and constructing new controllable synthesis methods for multifunctional fluorescent polymer nanomaterials with good water solubility and excellent biocompatibility is of great significance. Exploring efficient functionalization methods for luminescent materials is still one of the core issues in the design and development of new fluorescent materials. With this in mind, this review first introduces the structures, properties, and synthetic methods regarding fluorescent polymeric nanomaterials. Then, the functionalization strategies of fluorescent polymer nanomaterials are summarized. In addition, the research progress of multifunctional fluorescent polymer nanomaterials for bioimaging is also discussed. Finally, the synthesis, development, and application fields of fluorescent polymeric nanomaterials, as well as the challenges and opportunities of structure-property correlations, are comprehensively summarized and the corresponding perspectives are well illustrated.</description><identifier>ISSN: 1420-3049</identifier><identifier>EISSN: 1420-3049</identifier><identifier>DOI: 10.3390/molecules28093819</identifier><identifier>PMID: 37175229</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Biocompatibility ; biomedical imaging ; Biomedical materials ; Biosensors ; Coloring Agents ; Composite materials ; Controllability ; Drug delivery ; Drug Delivery Systems ; Fluorescence ; Free radicals ; Functional materials ; light-emitting polymer nanomaterials ; Medical imaging ; Methods ; Morphology ; Nanomaterials ; Nanoparticles ; Nanostructures - chemistry ; Nanotechnology ; organic fluorescent small molecule cell imaging ; Polymer industry ; Polymerization ; Polymers ; Polymers - chemistry ; Quantum dots ; R&D ; rare earth polymers ; Research & development ; Review ; semiconducting polymers</subject><ispartof>Molecules (Basel, Switzerland), 2023-04, Vol.28 (9), p.3819</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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They are widely used in biomedical fields such as bioimaging, biosensing, and drug delivery. Designing and constructing new controllable synthesis methods for multifunctional fluorescent polymer nanomaterials with good water solubility and excellent biocompatibility is of great significance. Exploring efficient functionalization methods for luminescent materials is still one of the core issues in the design and development of new fluorescent materials. With this in mind, this review first introduces the structures, properties, and synthetic methods regarding fluorescent polymeric nanomaterials. Then, the functionalization strategies of fluorescent polymer nanomaterials are summarized. In addition, the research progress of multifunctional fluorescent polymer nanomaterials for bioimaging is also discussed. Finally, the synthesis, development, and application fields of fluorescent polymeric nanomaterials, as well as the challenges and opportunities of structure-property correlations, are comprehensively summarized and the corresponding perspectives are well illustrated.</description><subject>Biocompatibility</subject><subject>biomedical imaging</subject><subject>Biomedical materials</subject><subject>Biosensors</subject><subject>Coloring Agents</subject><subject>Composite materials</subject><subject>Controllability</subject><subject>Drug delivery</subject><subject>Drug Delivery Systems</subject><subject>Fluorescence</subject><subject>Free radicals</subject><subject>Functional materials</subject><subject>light-emitting polymer nanomaterials</subject><subject>Medical imaging</subject><subject>Methods</subject><subject>Morphology</subject><subject>Nanomaterials</subject><subject>Nanoparticles</subject><subject>Nanostructures - chemistry</subject><subject>Nanotechnology</subject><subject>organic fluorescent small molecule cell imaging</subject><subject>Polymer industry</subject><subject>Polymerization</subject><subject>Polymers</subject><subject>Polymers - chemistry</subject><subject>Quantum dots</subject><subject>R&D</subject><subject>rare earth polymers</subject><subject>Research & development</subject><subject>Review</subject><subject>semiconducting polymers</subject><issn>1420-3049</issn><issn>1420-3049</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNplUstuFDEQHCEQecAHcEEjceGQDX6O7RNaAoFI4SEBZ8tjezZeeeyNPYO0f5_ebIgSkC1Vq7uq7G5107zC6JRShd6NOXo7R1-JRIpKrJ40h5gRtKCIqacP4oPmqNY1QgQzzJ83B1RgwQlRh03_0dewSiftz22ariCuJ61Jrv0Q8uhdsCa2y80mQjCFnNo8tF_nOIVhTnaXgPJ5nHPx1fo0tT9y3I6-tN9MyqOZfAkm1hfNswHAv7zD4-b3-adfZ18Wl98_X5wtLxeWUzotHAPgUlKBDOXcIM567wy2HaeKWtR5IqzkokeUOUOEVEoBDg6rXnKO6XFzsfd12az1poTRlK3OJujbRC4rbcoUbPQaIe7BibvOcaYEUwwjjhTuFDWMWwte7_dem7mHOeyaKyY-Mn1cSeFKr_IfjREWSokOHN7eOZR8Pfs66THAkGI0yee5aiIx5R2DC9Q3_1DXeS4w21sWEZQIJoF1umetDHQQ0pDhYQvH-THYnPwQIL-EZpCSXAkQ4L3Allxr8cP99zHSu_3R_-0PaF4_7Pte8Xdh6A2kacJx</recordid><startdate>20230429</startdate><enddate>20230429</enddate><creator>Bu, Qingpan</creator><creator>Li, Ping</creator><creator>Xia, Yunfei</creator><creator>Hu, Die</creator><creator>Li, Wenjing</creator><creator>Shi, Dongfang</creator><creator>Song, Kai</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-6477-6479</orcidid></search><sort><creationdate>20230429</creationdate><title>Design, Synthesis, and Biomedical Application of Multifunctional Fluorescent Polymer Nanomaterials</title><author>Bu, Qingpan ; 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subjects | Biocompatibility biomedical imaging Biomedical materials Biosensors Coloring Agents Composite materials Controllability Drug delivery Drug Delivery Systems Fluorescence Free radicals Functional materials light-emitting polymer nanomaterials Medical imaging Methods Morphology Nanomaterials Nanoparticles Nanostructures - chemistry Nanotechnology organic fluorescent small molecule cell imaging Polymer industry Polymerization Polymers Polymers - chemistry Quantum dots R&D rare earth polymers Research & development Review semiconducting polymers |
title | Design, Synthesis, and Biomedical Application of Multifunctional Fluorescent Polymer Nanomaterials |
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