Feasibility study of focused ultrasound in the treatment of vulvar low-grade squamous intraepithelial lesions with persistent symptoms

This study aimed to investigate the feasibility, efficacy, and safety of focused ultrasound (FUS) for the treatment of vulvar low-grade squamous intraepithelial lesions (VLSIL) with persistent symptoms. This retrospective analysis included 24 VLSIL patients who underwent FUS treatment. At each follo...

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Bibliographic Details
Published in:International journal of hyperthermia 2024-12, Vol.41 (1), p.2365975
Main Authors: Su, Chang, Liu, Xinglin, Wu, Can, Wang, Xi, Li, Chengzhi
Format: Article
Language:English
Subjects:
Adult
Aged
efficacy
feasibility
Feasibility Studies
Female
Focused ultrasound
Humans
Middle Aged
Retrospective Studies
safety
Squamous Intraepithelial Lesions - diagnostic imaging
Squamous Intraepithelial Lesions - pathology
Squamous Intraepithelial Lesions - therapy
Ultrasonic Therapy - methods
vulvar low-grade squamous intraepithelial lesions
Vulvar Neoplasms - diagnostic imaging
Vulvar Neoplasms - pathology
Vulvar Neoplasms - therapy
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Summary:This study aimed to investigate the feasibility, efficacy, and safety of focused ultrasound (FUS) for the treatment of vulvar low-grade squamous intraepithelial lesions (VLSIL) with persistent symptoms. This retrospective analysis included 24 VLSIL patients who underwent FUS treatment. At each follow-up visit, the clinical response was assessed including changes in symptoms and signs. In addition, the histological response was assessed based on the vulvar biopsy results of the 3rd follow-up. Clinical and histological response were assessed to elucidate the efficacy. A total of 22 patients completed follow-up and post-treatment pathological biopsies. After treatment, the clinical scores of itching decreased from 2.55 ± 0.51 to 0.77 ± 0.81 (  
ISSN:0265-6736
1464-5157
DOI:10.1080/02656736.2024.2365975