Embryonal rhabdomyosarcoma in a Siberian chipmunk (Tamias sibiricus): a case report

A 2-year-old female Siberian chipmunk (Tamias sibiricus) was presented to the veterinary clinic for swelling, pain and lameness of the left rear leg. Radiologically, an invasive tumour around the distal femur was suspected, and the leg was surgically amputated and submitted for histopathological dia...

Full description

Saved in:
Bibliographic Details
Published in:Veterinární medicína 2017-01, Vol.62 (9), p.527-531
Main Authors: Kong, J.Y., Kim, H.K., Lee, H.J., Yeon, S.C., Park, J.K., Jeong, K.S., Hong, I.H.
Format: Article
Language:English
Subjects:
Desmin
Femur
Leg
Metastases
Muscles
Myogenin
Myotubes
Nucleoli
Pain
ptah stain
Rhabdomyosarcoma
rodents
skeletal muscle
squirrel
Striations
Tamias sibiricus
Tumors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 2-year-old female Siberian chipmunk (Tamias sibiricus) was presented to the veterinary clinic for swelling, pain and lameness of the left rear leg. Radiologically, an invasive tumour around the distal femur was suspected, and the leg was surgically amputated and submitted for histopathological diagnosis. Microscopically, the mass was densely packed with multinucleated strap cells that had round-to-oval, or elongated nuclei with prominent nucleoli. These neoplastic cells occasionally formed myotubes with cross-striations and were immunohistochemically positive for muscle markers including desmin and myogenin. Consequently, embryonal rhabdomyosaroma myotubular variant of the leg with metastasis to the femur was diagnosed. Spontaneous rhabdomyosaromas are rare tumours in animals and humans, and this is the first report of its occurrence in a Siberian chipmunk.
ISSN:0375-8427
1805-9392
DOI:10.17221/173/2016-VETMED