Pediatric spinal glioblastoma of the conus medullaris:a case report of long survival

High?grade gliomas of the spinal cord represent a rare entity in children.Their biology,behavior,and controversial treatment options have been discussed in a few pediatric cases.These tumors are associated with severe disability and poor prognosis.We report a case of a 4?year?old child diagnosed wit...

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Bibliographic Details
Published in:Ai zheng 2016-05, Vol.35 (6), p.69-72, Article 44
Main Authors: Cacchione, Antonella, Mastronuzzi, Angela, Cefalo, Maria Giuseppina, Colafati, Giovanna Stefania, Diomedi‐Camassei, Francesca, Rizzi, Michele, De Benedictis, Alessandro, Carai, Andrea
Format: Article
Language:English
Subjects:
Cancer
cancer
Glioblastoma
Care and treatment
Case Report
Chemotherapy
Child, Preschool
Children
cord
Drug Therapy
Glioblastoma - pathology
Glioblastoma - therapy
Glioblastoma multiforme
Health aspects
Humans
Male
Multidisciplinary treatment
multiforme
Children
Multidisciplinary
Neurophysiology
Pediatrics
Prognosis
Radiotherapy
Radiotherapy, Adjuvant
Spinal
Spinal cord cancer
Spinal Cord Neoplasms - pathology
Spinal Cord Neoplasms - therapy
Treatment Outcome
treatment
Prognosis
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Summary:High?grade gliomas of the spinal cord represent a rare entity in children.Their biology,behavior,and controversial treatment options have been discussed in a few pediatric cases.These tumors are associated with severe disability and poor prognosis.We report a case of a 4?year?old child diagnosed with an isolated glioblastoma multiforme of the conus medullaris.The patient underwent subtotal surgical excision,followed by adjuvant radiotherapy and oral chem?otherapy.He is alive with mild neurologic deficits at 52 months after diagnosis.We describe the peculiar characteris?tics of this rare condition in pediatric oncology.We also provide an overview of current multidisciplinary therapeutic approaches and prognostic factors for this disease.
ISSN:1000-467X
2523-3548
1944-446X
1944-446X
2523-3548
DOI:10.1186/s40880-016-0107-1